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Background. There is increasing evidence that long-term exposure to fine particulate matter (PM2.5) may adversely impact cognitive performance. Wildfire smoke is one of the largest sources of PM2.5 today and concentrations are likely to increase under climate change. However, lit...

Municipal solid waste (MSW) landfills are a complex source where gaseous emissions depend both on operational and environmental factors. A campaign to detect and measure point source methane emissions from MSW landfills across the United States (U.S.) using a constellation of 12 ...

There is a need to assess compounds reliably and quickly for&nbsp;neurotoxicity&nbsp;(NT) and developmental neurotoxicity (DNT). Adverse outcome pathways (AOPs) enable the mapping of molecular events to an apical endpoint in a chemical agnostic manner and have begun to be applied...

EPA's Office of Research and Development (ORD) contributes a bi-annual guest column to the Journal of Environmental Health through a partnership with the National Environmental Health Association (NEHA). NEHA members include state, county, and city-level environmental public heal...

The Federal NanoEHS Community is having a discussion on wildfire smoke and wildfires that enter the wildland urban interface (WUI). As wildfires enter the WUI they burn human made structures and materials resulting in a different wildfire smoke mix. This invited presentation will...

This presentation (to GW graduate students in environmental health) will provide an overview of 1) the federal rulemaking process and public comments; 2) public comments in action; and 3) resources for writing timely and effective public comments. There will also be time for a di...

Background: Environmental epidemiologists strive to conduct research that will lead to actions that improve public health outcomes. The risk assessment process is the bridge between scientific research and policies that can impact public health. Historically, epidemiologic studie...

Considering wetland restoration at the regional, state, or watershed scale can provide targeted ecosystem services. Highly connected systems, particularly where hydrologic characteristics are foundational to the ecosystem, are more effective at providing ecosystem services compar...

As wildfire frequency and severity increases, smoke exposures will cause increasingly more adverse respiratory effects. While acute respiratory effects of smoke exposure have been documented in children, longer term sequelae are largely unstudied. Our objective here was to examin...

Background:&nbsp;Preterm birth (PTB; &lt;37 weeks completed gestation) is associated with exposure to air pollution, though variability in association magnitude and direction across exposure windows exists. We evaluated associations between weekly gestational exposure to fine par...

&nbsp; Background and Purpose: Thyroid Hormones (TH) production can be altered by Endocrine Disrupting Chemicals (EDCs). TH are essential to proper development, including that of the brain. TH are key to the differentiation of inhibitory interneurons including those expressing th...

Air pollution is a significant environmental health risk for urban areas and developing countries. Air pollution may contribute to the incidence of cardiopulmonary and metabolic diseases. Evidence also points to the role of air pollution in worsening or developing neurological an...

The public health community recognizes the need to increase attention to maternal health conditions, with hypertensive disorders of pregnancy (e.g., preeclampsia) at the forefront. Pregnancy is a significant cardiovascular stressor due to the dramatic increases in the maternal bl...

The goal of the research under the Federal Research Action Plan on Recycled Tire Crumb Used on Playing Fields and Playgrounds (FRAP) is to characterize potential human exposures to the substances associated with recycled tire crumb rubber used on synthetic turf fields. The result...

New approach methodologies (NAMs) are being evaluated for their utility to inform developmental neurotoxicity (DNT) hazard instead of using animals. The integration of in vitro assays, representing diverse neurodevelopmental processes, will be a critical next step for evaluating ...

Exposure to ambient fine particulate matter (PM2.5) was found to produce vascular injury, possibly by activating platelets within days after exposure. The aim of this study was to investigate the modulatory effects of dietary saturated fatty acids on platelet mitochondrial respir...

Climate change has been associated with increased incidence and severity of wildland fires. With firefighters at greatest risk and in an occupation dominated by males of reproductive age, it is important to understand not only cardiopulmonary risks but reproductive health as well...

Rationale &amp; Objectives: Wildfire smoke is associated with short-term respiratory outcomes including asthma exacerbation in children. As investigations into developmental exposure to wildfire smoke exposure (WSE) on children&rsquo;s longer-term respiratory health are sparse, w...

Fine particle pollution is a well-established risk to human health. Observational epidemiology generally treats events as though they are independent of one another and so do not examine the role air pollution may play in promoting the progression of disease. Multistate survival ...

Presentation of research examining daily temperature differences in association with risk of preterm birth using a North Carolina cohort.&nbsp;

This is a guest lecture for UNC-Chapel Hill course ENVR400, providing my personal and academic background, as well as an overview of EPA and highlights of my research at EPA. Students should gain a better understanding of environmental epidemiology research at EPA, as well as lea...

New approach methods (NAMs) are being evaluated for their ability to inform developmental neurotoxicity (DNT) hazard potential. The Organisation for Economic Co-operation and Development (OECD), in collaboration with the European Food Safety Agency, United States Environmental Pr...

Environmental health concerns over per- and polyfluoroalkyl substances (PFAS) have prompted public health laboratories to pursue monitoring studies determining PFAS occurrences. Select laboratories have begun implementing Non-Targeted Analysis (NTA) methods to address the dispari...

Continued improvements in drinking-water quality characterization and treatment/distribution infrastructure are required to address the expanding number of documented environmental contaminants. To better understand the variability in contaminant exposures from the drinking water...

Background and Purpose: Environmental exposure to pollutants combined with unhealthy diet can increase the risk of adverse health effects. Such effects can be more serious if the exposure scenario occurs during early life stages. This study evaluated the effects of maternal Cd ex...